A 21 year old man was due to appear in court in Douglas today charged with murder and attempted murder.
Police attended a property in Andreas in the early hours of Sunday morning and found the body of a woman.
Police say there is no risk to the general public and say enquiries will continue in the Andreas area in the coming days and weeks.
A statement has been issued by Detective Inspector Michelle McKillop, who said: “At this time only limited information can be given about the circumstances surrounding this tragic loss of life and the impact this whole event is having on the family and friends of all of those involved.
“I want to urge the public not to speculate on social media as to the events or those involved as there is a need to protect the investigation and any subsequent proceedings and also to be respectful towards the family at this dreadful time.
“Murders are rare on the Isle of Man, we are more fortunate than many to live in a safe community, but these events do occur and when they do we will do everything within our power to ensure we do the best we possibly can to support the family and to investigate the matter thoroughly.”